Research Updates
  • Flax Hull Lignans have an Oxygen Radical Absorbance Capacity (ORAC) value of 19,600!
  • High lignan diet linked to Health Benefits.
  • Most of us do not get enough lignans.
  • Lignans have 5 times stronger in Antioxidant activity compared to Vitamin-E.
  • Lignans are as effective as hormone replacement therapy in reducing mild menopausal symptoms without side effects.
  • High Lignan diet reduce risk of Breast Cancer.
  • Lignans inhibit prostatic 5 alpha reductase upto 80% to reduce size of enlarged prostrate.
  • Lignans reduce hair loss.
  • Lignan reduce acne (pimples).
  • Lignans help reduce weight.
  • Lignans Flush away harmful toxins.
  • Lignans help lose weight and flatten the stomach.
  • Lignans help reduce skin wrinkles.
     
 
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Lignoflax
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Content per pack : 60 capsules in a bottle.
Composition : Flax Seed Hull 500mg eq. to SDG lignans 22mg.
Recommended Serving : Take 1 capsule with breakfast and 1 capsules with dinner.
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Reduces Acne

Acne vulgaris (cystic acne or simply acne) is a common human skin disease, characterized by areas of skin with seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules (pinheads), pustules (pimples), nodules (large papules) and possibly scarring.[1] Acne affects mostly skin with the densest population of sebaceous follicles; these areas include the face, the upper part of the chest, and the back. Severe acne is inflammatory, but acne can also manifest in noninflammatory forms.The lesions are caused by changes in pilosebaceous units, skin structures consisting of a hair follicle and its associated sebaceous gland, changes that require androgen stimulation.

Acne occurs most commonly during adolescence, and often continues into adulthood. In adolescence, acne is usually caused by an increase in testosterone, which accrues during puberty, regardless of sex.[3] For most people, acne diminishes over time and tends to disappear — or at the very least decreases — by age 25.[4] There is, however, no way to predict how long it will take to disappear entirely, and some individuals will carry this condition well into their thirties, forties, and beyond.

Some of the large nodules were previously called "cysts" and the term nodulocystic has been used to describe severe cases of inflammatory acne.[6] The "cysts", or boils that accompany cystic acne, can appear on the buttocks, groin, and armpit area, and anywhere else where sweat collects in hair follicles and perspiration ducts.[7] Cystic acne affects deeper skin tissue than does common acne.[8] Aside from scarring, its main effects are psychological, such as reduced self-esteem[9] and in very extreme cases, depression or suicide.[10] Acne usually appears during adolescence, when people already tend to be most socially insecure. Early and aggressive treatment is therefore advocated by some to lessen the overall long-term impact to individuals.

Signs and symptoms

Acne scars are the result of inflammation within the dermis brought on by acne. The scar is created by the wound trying to heal itself resulting in too much collagen in one spot.[15] Physical acne scars are often referred to as "ice pick" scars. This is because the scars tend to cause an indentation in the skin's surface. There is a range of treatments available. Although quite rare, the medical condition atrophia maculosa varioliformis cutis also results in "acne-like" depressed scars on the face.

Ice pick scars: Deep pits, that are the most common and a classic sign of acne scarring. Box car scars: Angular scars that usually occur on the temple and cheeks, and can be either superficial or deep, these are similar to chickenpox scars. Rolling scars: Scars that give the skin a wave-like appearance. Hypertrophic scars: Thickened, or keloid scars.

Pigmentation

Pigmented scars is a slightly misleading term, as it suggests a change in the skin's pigmentation and that they are true scars; however, neither is true. Pigmented scars are usually the result of nodular or cystic acne (the painful 'bumps' lying under the skin). They often leave behind an inflamed red mark. Often, the pigmentation scars can be avoided simply by avoiding aggravation of the nodule or cyst. Pigmentation scars nearly always fade with time taking between three months to two years to do so, although can last indefinitely if untreated.

Cause

Acne develops as a result of blockages in the follicles. Hyperkeratinization and formation of a plug of keratin and sebum (a microcomedo) is the earliest change. Enlargement of sebaceous glands and an increase in sebum production occur with increased androgen (DHEA-S) production at adrenarche. The microcomedo may enlarge to form an open comedone (blackhead) or closed comedone (milia). Comedones are the direct result of sebaceous glands' becoming clogged with sebum, a naturally occurring oil, and dead skin cells. In these conditions, the naturally occurring largely commensal bacterium Propionibacterium acnes can cause inflammation, leading to inflammatory lesions (papules, infected pustules, or nodules) in the dermis around the microcomedo or comedone, which results in redness and may result in scarring or hyperpigmentation.

Hormonal

Hormonal activity, such as menstrual cycles and puberty, may contribute to the formation of acne. During puberty, an increase in sex hormones called androgens cause the follicular glands to grow larger and make more sebum.[17] Use of anabolic steroids may have a similar effect.[18] Several hormones have been linked to acne: the androgens testosterone, dihydrotestosterone (DHT) and dehydroepiandrosterone sulfate (DHEAS), as well as insulin-like growth factor 1 (IGF-I).

Development of acne vulgaris in later years is uncommon, although the incidence of rosacea, which may have a similar presentation, is increased in older age groups. True acne vulgaris in adult women may be a feature of an underlying condition such as pregnancy, or disorders such as polycystic ovary syndrome and Cushing's syndrome. Menopause-associated acne (known as acne climacterica) occurs as production of the natural anti-acne ovarian hormones estradiol and progesterone fail, permitting the acnegenic hormone testosterone to exert its effects unopposed.

Genetic

The predisposition for specific individuals to acne is likely explained by a genetic component, which has been supported by twin studies as well as studies that have looked at rates of acne among first degree relatives. The genetics of acne susceptibility is likely polygenic, as the disease does not follow classic Mendelian inheritance pattern. There are multiple candidates for genes which are possibly related to acne, including polymorphisms in TNF-alpha, IL-1 alpha, CYP1A1 among others.

Psychological

While the connection between acne and stress has been debated, scientific research indicates that "increased acne severity" is "significantly associated with increased stress levels."[20] The National Institutes of Health (USA) list stress as a factor that "can cause an acne flare."[21] A study of adolescents in Singapore "observed a statistically significant positive correlation … between stress levels and severity of acne.

Infectious

Propionibacterium acnes (P. acnes) is the anaerobic bacterium species that is widely concluded to cause acne, though Staphylococcus epidermidis has been universally discovered to play some role since normal pores appear colonized only by P. acnes.[23] Regardless, there are specific clonal sub-strains of P. acnes associated with normal skin health and others with long-term acne problems. It is as yet inconclusive whether any of these undesirable strains evolve on-site in the adverse conditions or are all pathogenically acquired, or possibly both depending on the individual patient. These strains either have the capability of changing, perpetuating, or adapting to, the abnormal cycle of inflammation, oil production, and inadequate sloughing activities of acne pores. At least one particularly virulent strain, though, has been circulating around Europe for at least 87 years. In vitro, resistance of P. acnes to commonly used antibiotics has been increasing, as well

Diet

A high glycemic load diet is associated with worsening acne.[26][27] There is also a positive association between the consumption of milk and a greater rate and severity of acne.[26][28] The role of chocolate is controversial, with recent studies finding a relationship between chocolate consumption and acne exacerbation.[29][30][31] Chocolate contains a varying amount of sugar that can lead to a high glycemic load, and it can be made with or without milk in one form or another (see types of chocolate).

A 2010 review study found that after reviewing existing studies of the relationship between diet and acne, "there are no answers but there are definitely more questions, because there is no clear proof about whether these issues are facts or misconceptions". There is evidence to suggest that there is a relationship between acne and insulin metabolism, while a dated study found a correlation between acne and obesity.

Diagnosis

There are multiple scales for grading the severity of acne vulgaris,[34] three of these being: Leeds acne grading technique: Counts and categorises lesions into inflammatory and non-inflammatory (ranges from 0–10.0).

Cook's acne grading scale: Uses photographs to grade severity from 0 to 8 (0 being the least severe and 8 being the most severe).

Pillsbury scale: Simply classifies the severity of the acne from 1 (least severe) to 4 (most severe).

Lignoflax health benefits for men and women:
  • Reduce Acne
 
 
     
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LignoFlax Can Help:
 
Prevents Breast Cancer        Prevents Prostrate Cancer        Lignans for Hair Loss        Reduces Acne        Reduces pimples        Improves Heart
 
Improves Liver Function        Improves body immunity        Lose weight        Reduces negative response to stress        More About Lignans
 
Improves polycystic Ivarian Syndrome Symptoms        Skin wrinkles        Antioxidant        High ORAC (Oxygen Radical Absorbance Capacity)
 
Detox the body        Diabetes        Improves Memory        Increase Height
   
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