Research Updates
  • Flax Hull Lignans have an Oxygen Radical Absorbance Capacity (ORAC) value of 19,600!
  • High lignan diet linked to Health Benefits.
  • Most of us do not get enough lignans.
  • Lignans have 5 times stronger in Antioxidant activity compared to Vitamin-E.
  • Lignans are as effective as hormone replacement therapy in reducing mild menopausal symptoms without side effects.
  • High Lignan diet reduce risk of Breast Cancer.
  • Lignans inhibit prostatic 5 alpha reductase upto 80% to reduce size of enlarged prostrate.
  • Lignans reduce hair loss.
  • Lignan reduce acne (pimples).
  • Lignans help reduce weight.
  • Lignans Flush away harmful toxins.
  • Lignans help lose weight and flatten the stomach.
  • Lignans help reduce skin wrinkles.
     
 
Deccan Healthcare
Lignoflax
NOW FOR Rs360/- Per pack
NOW FOR $6/- Per pack Out Side India
Availability - In Stock
Content per pack : 60 capsules in a bottle.
Composition : Flax Seed Hull 500mg eq. to SDG lignans 22mg.
Recommended Serving : Take 1 capsule with breakfast and 1 capsules with dinner.
  Reviews Write a Review
High ORAC (Oxygen Radical Absorbance Capacity)

Oxygen radical absorbance capacity (ORAC) is a method of measuring antioxidant capacities in biological samples in vitro.

A wide variety of foods has been tested using this method, with certain spices, berries and legumes rated highly in extensive tables once published by the United States Department of Agriculture (USDA), but withdrawn in 2012 as biologically invalid, stating that no physiological proof in vivo existed in support of the free-radical theory. Consequently, the ORAC method, derived only in in vitro experiments, is no longer considered relevant to human diets or biology by the USDA.

Although not all have been unilaterally dismissive, the majority position supports the USDA decision. Alternative measurements include the Folin-Ciocalteu reagent, and the Trolox equivalent antioxidant capacity assay.

Method

The assay measures the oxidative degradation of the fluorescent molecule (either beta-phycoerythrin or fluorescein) after being mixed with free radical generators such as azo-initiator compounds. Azo-initiators are considered to produce the peroxyl radical by heating, which damages the fluorescent molecule, resulting in the loss of fluorescence. Antioxidants are considered to protect the fluorescent molecule from the oxidative degeneration. The degree of protection is quantified using a fluorometer. Fluorescein is currently used most as a fluorescent probe. Equipment that can automatically measure and calculate the capacity is commercially available (Biotek, Roche Diagnostics).

The fluorescent intensity decreases as the oxidative degeneration proceeds, and this intensity is typically recorded for 35 minutes after the addition of the azo-initiator (free radical generator). So far, AAPH (2,2’-azobis(2-amidino-propane) dihydrochloride) is the sole free-radical generator used. The degeneration (or decomposition) of fluorescein is measured as the presence of the antioxidant slows the fluorescence decay. Decay curves (fluorescence intensity vs. time) are recorded and the area between the two decay curves (with or without antioxidant) is calculated. Subsequently, the degree of antioxidant-mediated protection is quantified using the antioxidant trolox (a vitamin E analogue) as a standard. Different concentrations of trolox are used to make a standard curve, and test samples are compared to this. Results for test samples (foods) have been published as "trolox equivalents" or TEs.

One benefit of using the ORAC method to evaluate substances' antioxidant capacities is that it takes into account samples with and without lag phases of their antioxidant capacities. This is especially beneficial when measuring foods and supplements that contain complex ingredients with various slow- and fast-acting antioxidants, as well as ingredients with combined effects that cannot be precalculated.

Drawbacks of this method are: 1) only antioxidant activity against particular (probably mainly peroxyl) radicals is measured; however, peroxyl radical formation has never been proven; 2) the nature of the damaging reaction is not characterized; 3) there is no evidence that free radicals are involved in this reaction; and 4) there is no evidence that ORAC values have any biological significance following consumption of any food. Moreover, the relationship between ORAC values and a health benefit has not been established.

Resulting from scientific refutation of the physiological significance of ORAC, the USDA, which had been collating and publishing ORAC data for more than a decade, withdrew its web publication of ORAC values for common American foods in May 2012.

Several modified ORAC methods have been proposed. Most of them employ the same principle (i.e. measurement of AAPH-radical mediated damage of fluorescein); however, ORAC-EPR, electron paramagnetic resonance-based ORAC method directly measures the decrease of AAPH-radical level by the scavenging action of the antioxidant substance.

Regulatory guidance

In the following discussion, the term "antioxidant" refers mainly to non-nutrient compounds in foods, such as polyphenols, which have antioxidant capacity in vitro, so provide an artificial index of antioxidant strength—the ORAC measurement.

Other than for dietary antioxidant vitamins -- vitamin A, vitamin C and vitamin E -- no food compounds have been proved with antioxidant efficacy in vivo. Accordingly, regulatory agencies such as the Food and Drug Administration of the United States and the European Food Safety Authority (EFSA) have published guidance disallowing food product labels to claim or imply an antioxidant benefit when no such physiological evidence exists.[9][10] This guidance for the United States and European Union establishes it is illegal to imply potential health benefits on package labels of products with high ORAC.

Food sources

Values are expressed as the sum of the lipid soluble (e.g. carotenoid) and water-soluble (e.g. phenolic) antioxidant fractions (i.e., “total ORAC”) reported as in micromoles trolox equivalents (TE) per 100 gram sample, and are compared to assessments of total polyphenol content in the samples.

Comparisons of ORAC values

The United States Department of Agriculture, previously a publisher of ORAC data, withdrew its web publication of ORAC values for common American foods in 2012 due to absence of scientific evidence that ORAC has any biological significance.

When comparing ORAC data, care must be taken to ensure the units and food being compared are similar. Some evaluations will compare ORAC units per gram of dry weight, others will evaluate ORAC units in wet weight and still others will look at ORAC units per serving. Under each evaluation, different foods can appear to have higher ORAC values. For example, although a raisin has no more antioxidant potential than the grape from which it was dried, raisins will appear to have a higher ORAC value per gram of wet weight than grapes due to their reduced water content. Likewise, the large water content in watermelon can make it appear as though this fruit is low in ORAC. Similarly, the typical quantity of food used should be considered; herbs and spices may be high in ORAC, but are applied in much smaller quantities than for other foods.

Numerous health food and beverage companies and marketers have erroneously capitalized on the ORAC rating by promoting products claimed to be "high in ORAC". As most of these ORAC values have not been independently validated or subjected to peer review for publication in scientific literature, they remain unconfirmed, are not scientifically credible, and may mislead consumers.

Lignoflax health benefits for men and women
  • High ORAC both men and women
 
     
E-mail us:mailbox@deccanhealth.com   +91-40-3914 0000 ( Monday to Friday --11 AM to 6PM)
 
LignoFlax Can Help:
 
Prevents Breast Cancer        Prevents Prostrate Cancer        Lignans for Hair Loss        Reduces Acne        Reduces pimples        Improves Heart
 
Improves Liver Function        Improves body immunity        Lose weight        Reduces negative response to stress        More About Lignans
 
Improves polycystic Ivarian Syndrome Symptoms        Skin wrinkles        Antioxidant        High ORAC (Oxygen Radical Absorbance Capacity)
 
Detox the body        Diabetes        Improves Memory        Increase Height
   
© Lignoflax All rights reserved  
                   
deccan-logo cgmp-logo logo-3 deccanhealthcare logo5 safe Natural logo9 wellness-logo

 

   NO DEAL FOR THE DAY
   
buy
     
Deccanprofile buy
CONTACT CUSTOMER SERVICES
Email ID : mailbox@deccanhealth.com
Phone No : +91-40-3914 0000 ( Monday to Friday -- 11AM to 6PM)
ADDRESS
Corporate Office :
Plot No. 8-2-293/82/J111/564A-22/1,
Road No. 92, Jubilee Hills,
Aakanksha Building,
Hyderabad - 500 033 , A.P., India.